I know what you're thinking, this man is insane how can there be known problems for a vehicle not even in showrooms yet! You're right how can there be? What we do know however are the known problems with the NV200, The City Express' donor vehicle. Since the NV200 has been on the market for a little over 3 years it gives us a healthy sample of information to consider!
Keep in mind some of the issues may of been corrected with the Chevrolet, however they are still things to keep in mind.
First up is warranty,
I know for a FACT that the lifetime warranty offered on the NV200 is not applicable should your van be used for commercial or fleet purposes. I do believe that the warranty on City Express differs from NV200, regardless consult your salesperson and the fine print to confirm that warranty is still applicable to your commercial/fleet City Express.
The NV200 has a faulty brake light switch which is prone to letting go which leads to ABS and Traction Control disabling and flashing both warning lights. Considering the City Express will be using all Nissan electric systems I believe this is one to watch for.
NV200 owners have expressed issues with the bluetooth functions. The microphones are prone to fizzling out. I know that the CIty Express will be using GM OnStar software in the headunit but I'm not sure if there were any alterations made to the physical components.
There was a slight airbag issues with Canadian NV200's, the front passenger air bags would not inflate in the event of a collision. This has been an issue with several Nissan vehicles.
Above all the main problem with the NV200 has been its inability to tow, something that will not go away on the City Express either.
Instead of taking this list as a negative you should see it as reinforcement of the quality product we are being offered. In over 3 years on the market these are the assortment of niggles accumulated. So if you can get past the lack of towing you should be highly satisfied with the City Express, I know NV200 people are.